Final presentation schedule was set on Sept 15, 2022.
Schedule of Events
Friday, September 30, 2022
Pre-conference events
Chemistry Atrium and A. Paul Schaap Lecture Hall
3:30 – 4:30 pm Dr. Pam Marino (National Institutes of Health), “Glycomics & the Glycosciences: a Program Directors Perspective on Building Infrastructure for an OMICS Field” as the WSU Biochemistry Seminar
4:30 – 6:15 pm Meeting Registration; Poster Setup
Session I – Sugars in Disease
A. Paul Schaap Lecture Hall
Chair: Peter Andreana (University of Toledo)
6:25 – 6:30 pm – Introductory Remarks – Charlie Fehl and Hien Nguyen
6:30 – 7:00 pm – Nicole Koropatkin (University of Michigan): Towards understanding how human gut Bacteroides respond to a drug for type 2 diabetes
7:00 – 7:15 pm – Garry Leonard (Wayne State University): Synthesis and mammalian cell compatibility of light-released glycan precursors for controlled metabolic engineering
7:15 – 7:30 — Kezhong Zhang (Wayne State University School of Medicine): Effects and Mechanisms of Heparan Sulfate-Mimicking Compounds in Attenuating Stress Response and Inflammation associated with Diabetes and Alzheimer’s Disease (I)
7:30 – 7:45 pm – Min-Hao Kuo (Michigan State University): Effects and Mechanisms of Heparan Sulfate-Mimicking Compounds in Attenuating Stress Response and Inflammation associated with Diabetes and Alzheimer’s Disease (II)
7:45 – 8:15 pm – Break, Poster Session – A. Paul Schaap Chemistry Building – Atrium
8:15 – 8:30 pm – Priscilla Dzigba (Central Michigan University): Host-directed immune targeting of mycobacteria through cell surface glycan engineering
8:30 – 9:00 pm – Steve Sucheck (University of Toledo): Synthesis of antigenic polysaccharides of P. aeruginosa and progress towards a P. aeruginosa vaccine
9:00 pm – Reception, Poster Session
Food and beverages provided.
Saturday, Oct 1, 2022
7:30 – 8:15 am – Continental Breakfast – A. Paul Schaap Chemistry Building – Atrium
Session II – Synthesis
A. Paul Schaap Lecture Hall
Chair: Weiping Tang (University of Wisconsin at Madison)
8:15 – 8:45 am – Nicola Pohl (Indiana University): Strategies for Automated Glycan Synthesis
8:45 – 9:00 am – Prem Gurung (University of Toledo): Development of a New Cationic Gold(I)-Catalyzed Glycosylation Method
9:00 – 9:30 am – Eric Sletten (Max Planck Institute of Colloids and Interfaces): Expanding the automated glycan assembly toolbox
9:30 – 9:45 am – Radhika Thanvi (University of Toledo): Carbasugar-based Potential Maltoside Inhibitors for Mycobacterium tuberculosis GlgE
9:45 – 10:45 am – Break, Poster Session
10:45 – 11:15 am – Jianglong Zhu (University of Toledo): Stereoselective Anomeric O-Alkylation: A Viable Alternative to Conventional Glycosylation
11:15 – 11:30 am – Abram Axelrod (Purdue University): Organocatalytic Stereoselective Koenigs-Knorr Glycosylations
11:30 – noon – Pavel Nagorny (University of Michigan): New catalytic methods and approaches for the synthesis of carbohydrates and glycosylated natural products
noon – 1:45 pm – Lunch, Poster Session
Session III – Glycobiology
A. Paul Schaap Lecture Hall
Chair: Pam Marino (NIH)
1:45 – 2:15 pm – Charlie Fehl (Wayne State University): Chemical strategies for capturing dynamic O-GlcNAc protein glycosylation events in live cells
2:15 – 2:30 pm – Isaac Turan (Cleveland State University): Synthesis of Sialidase Inhibitors with Different Polarities and Their Anti-Coronavirus Replication Activities
2:30 – 3:00 pm – Stephanie Olivier-Van Stichelen (Medical College of Wisconsin): O-GlcNAcylation as a driver of sexual dimorphism in gestational diabetes
3:00 – 3:30 pm – Break, Poster Session
3:30 – 3:45 pm – Hawau Abdulsalam (Wayne State University): Development of Sulfated Glycopolymers as attachment factors for SARS-CoV-2
3:45 – 4:15 pm – Ben Swarts (Central Michigan University): Chemical probes for mycobacterial glycans: from tools to therapeutic opportunities
4:15 – 4:30 pm – Christopher M. Stevens (University of Wisconsin-Madison): Synthesis of Mannose-6-Phosphonate Conjugate for Targeted Protein Degradation through the Lysosome
4:30 – 5:00 pm – Xuefei Huang (Michigan State University): Expedient Synthesis of Extensive Heparan Sulfate Oligosaccharide Libraries
5:00 – 5:30 pm – Awards, Concluding Remarks
5:30 – 6:15 pm – Poster Breakdown
6:15 pm – Dinner
List of Posters
Babatunde S. Obadawo Toledo Optimizing Photocleavable Linkers for Oligosaccharide Synthesis
Cameron Talbot + Xingling Pan MSU Targeting and development of a potential broad spectrum Salmonella vaccine
Chia-Wei Yang MSU Indocyanine Green Conjugated Superparamagnetic Iron Oxide Nanoworm for Multimodality Breast Cancer Imaging
Cyrus Alan Lee Wayne Phenanthroline-Catalyzed 1,2-cis S-linked glycosylations
Dan Corey Wayne Design and synthesis of Sox2 fusion constructs and photoactive glycopeptides for analysis of O-GlcNAc specific Protein-protein interactions
Daniel H. Swanson CMU Synthesis and evaluation of small trehalose–fluorophore conjugates as potential probes for bacterial trehalose uptake
Elizabeth Davis Indiana University Exploring the Use of Hafnium in Activating Highly Hindered Anhydrides in the Acylation of Alcohols and Carbohydrate-Derived Polyols
Fenglang Wu Toledo Synthesis of a Hexasaccharide Repeating Unit of Bacillus anthracis Vegetative Cell Walls
Ishani V. Gaidhane Central Chain-truncated trehalose mycolate derivatives for chemical remodeling of the mycobacterial outer membrane
Jayanta Ghorai Wayne Carbohydrate Vaccine Adjuvants
Jessica Groenevelt Wayne Synthesis and structural analysis of 5′-pivaloyl pseudouridine, a site-selective radical nucleoside precursor.
Karishma Kalera Central Azido- and amino-trehalose inhibitors to study and target trehalose metabolic remodeling in mycobateria
Kyle Biegas CMU Photoactivatable glycolipid probes for identifying mycolate-protein interactions in live mycobacteria
Majdi Aljohani Cleveland State Systemic Profiling of Desialylation of Monocytes and Macrophages upon LPS stimulation
Mattieu Lucas Geremia Toledo Indirect quantification of 5-hydroxymethylcytosine (5-hmC)
Morgan Mayieka MSU Development of a synthetic strategy to prepare mimetics of heparan sulfate
Noah Davis Indiana University Exploring the Use of Tin in Activating Dihydropyran in the
Tetrahydropyranylation of Alcohols and Polyols
Nolan Carney Umich Synthesis of 2-deoxyglycoside Containing Cardiotonic Steroids Oleandrin and Beaumontoside
Oleksii Zhelavskyi Umich Regioselective Acetalization Catalyzed with Polymer-Supported Chiral Phosphoric Acids and Its Application to Single-Pot Synthesis of Differentially Protected Saccharides
Po-Han Lin MSU Facile synthesis of glycopeptide bearing tetrasaccharide linkage region and chondroitin sulfate
Ryan Rutkoski Umich Solid-supported Phosphonates as Recyclable Leaving Groups for Glycosylations
Saheed A. Ayodeji Wayne Aberrant glucose metabolism implicated in triple negative breast cancer stem cell pathway through OGT-TET1-TARDBP axis
Saniya Shehbaz Khan Toledo Synthesis and inhibition studies of trehalose analogs for the inhibition Ag85 complex in Mycobacterium tuberculosis.
Sherif Ramadan MSU Chemical synthesis of Pertussis core Pentasaccharide as Potential Anti-pertussis Vaccines
Sherif Ramadan (2nd abstract) MSU Synthesis of a Large, Comprehensive Heparan Sulfate (HS) Library from Solution Phase to Automation on Solid Phase
Somnath Bhagat MSU Development of heparan sulfate mimetics for inhibition of HMGB-1 protein
Sungjin Kim Umich Synthesis of Glycosyl Fluorides using Photo- and Electro-Activation of Sulfur(VI) Hexafluoride
Ulysses Johnson Central Characterization of trehalose analogues’ hydrolytic resistance and their potential use as inhibitors of trehalose utilization in microorganisms
Umesha Kumbalathara Toledo Synthesis and Evaluation of an Antitubercular Chemical Probe Derived from 2-aminothiophene and Conjugation with Trehalose
Uzoamaka Bokolo Toledo Progress towards a polymer supported synthesis of Pseudomonas aeruginosa exopolysacharide (Psl)
Xiaohua Li Umich-Dearborn Synthesis of trisaccharide oligomer of Salmonella E1 capsular polysaccharide via anomeric O–alkylation involving L-sugar-derived electrophiles
Late-breaking Posters
Shanika Gamage Toledo Microwave-Assisted Glycosylation Reactions in the Absence of Activators
Joseph Wakpal Wayne State Design and synthesis of aminoglycoside-based heparan sulfate mimetics as heparanase inhibitors
Lalitha Gummidi Indiana ADVANCES TOWARDS COMPLEX POLYSACCHARIDES AND PEPTIDOGLYCANS USING AUTOMATED FLOW CHEMISTRY
Joe Jose Pavarttikaran Indiana Development of Automated Flow Methods for O-Debenzylation of Carbohydrates
Naveed Khan Indiana Development of a Convergent Synthesis of Xyloglucan Fragments Using Automated Flow Chemistry
Rose Schnabel Indiana University Towards the automated flow synthesis and in-line FSPE purification of fluorous-tagged disaccharides
Prashant Kumar Indiana University AUTOMATED FLOW SYNTHESIS OF GLYCOSYLATED AMINO ACIDS
FOR C TO N AND N TO C SOLID PHASE PEPTIDE SYNTHESIS (SPPS)
Naresh Vennetti Wayne State Photo and Catalytic Desulfurizations: Application to Organic Molecules, Peptides and Proteins