Dr. Hans Hummer’s presentation covers the First and Second Pandemics of the Bubonic plague in Late Antiquity and the Middle Ages. It explores three pandemics of Bubonic Plague that took place. The first, the Justinianic Plague of the sixth century, lasted 200 years. The second, The Black Death in the fourteenth century, is the deadliest pandemic in recorded history.
Link to presentation: Pandemic Perspectives — Bubonic Plagues in the Middle Ages

Image credit: Painting shows Florence as imagined in 1348 under the Black Death, although it was created centuries later. Image courtesy of Wiki Commons and is in the public domain.