Research in the Pflum Group integrates organic chemistry, biochemistry, and cell biology to understand the molecular basis of disease. For many years, we have been particularly interested in two proteins associated with cancer formation: kinase and histone deacetylase enzymes. Our goal is to use a chemical approach to characterize the role of these proteins in cancers, which will lead to the identification of novel drugs targeting these proteins and biomarkers to diagnose illness.
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2025
2024
2023
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