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The Greenberg lab is currently recruiting graduate students! Click here to learn more about the unique opportunities our lab has to offer!
What we do:
It is estimated that nearly half (45%) of people in the United States suffer from at least one chronic disease. In order to better understand these diseases and identify potential treatments, a fundamental challenge for scientists is to develop suitable research models for studying them. Cells represent the most basic unit of life, and thus many human diseases result from functional/metabolic irregularities at the cellular level. Due to the multitude of well-established genetic, biochemical, and molecular methods for monitoring cellular function, cell models provide an excellent system for studying disease. In our lab, we use a variety of complementary human, mouse, rat, and yeast cell lines to explore the intricacies of mitochondrial function and metabolism with the goal of identifying potential therapeutic targets for two chronic diseases, bipolar disorder (BD) and Barth syndrome (BTHS).