05/2020: Our group paper in collaboration with the Luo and Schlegel groups here at Wayne State University, “Diastereoselective sp3 C-O Bond Formation via Visible Light-Induced, Copper-Catalyzed Cross Couplings of Glycosyl Bromides with Aliphatic Alcohols,” has been published in ASAP in ACS Catalysis. Congratulations, Fei, Jalen, Ravi, Hengfu, and Richard!
04/2020: Our group paper in collaboration with the Zhang group here at Wayne State University School of Medicine and with the Vlodavsky group at Technion, “Modulating Heparanase Activity: Tuning Sulfation Pattern and Glycosidic Linkage of Oligosaccharides”, has been published in Journal of Medicinal Chemistry. Congratulations Sanyong, Jiayi, and Ravi!
04/2020: The group received another NIH R01 grant to support our sulfated aminoglycan project! Thank you everyone for your hard work.
12/2019: Congratulations to Jason Mixdorf for successfully defending his Ph.D. thesis. Best of luck with your new adventure in the lab of Prof. Brad Christian at the Alzheimer’s Disease Research Center, University of Wisconsin at Madison. Good luck, Dr. Mixdorf!
12/2019: We welcome first year graduate students: Connor, Chenlu, Fuad, and Joseph to the Nguyen group!
10/2019: Our group paper in collaboration with the Stockdill group here at Wayne State University, “Facile Triflic-Acid-Catalyzed alpha-1,2-Cis-Thiol Glycosylations: Scope and Application to the Synthesis of S-Linked Oligosaccharides, Glycolipids, Sublancin Glycopeptide, and Tn/Tf Antigens”, has been accepted for publication in Chemical Science. Congratulations Sanyong, Ganesh, and Eric!
08/2019: Our NIH R01 grant has been renewed to support our heparanase project in the lab!!!
08/2019: Our group paper in collaboration with the Gutierrez group at University of Maryland, “The Role of Trichloroacetimidate To Enable Iridium-Catalyzed Regio- and Enantioselective Allylic Fluorination: A Combined Experimental and Computational Study” has been accepted for publication in JACS. Congratulations Alexandre and Jason!
04/2019: Our group paper in collaboration with the Schlegel group here at Wayne State University, “Phenanthroline-Catalyzed Stereoretentive Glycosylations.” has been published in early review in Angewandte Chemie International Edition. Congratulations to Fei, Jiayi, Paul, and Tu!
02/2019: Our group paper in collaboration with the Schlegel group here at Wayne State University, “Are Brønsted Acids the True Promoter of Metal Triflate Catalyzed Glycosylations? A Mechanistic Probe into 1,2-cis-Aminoglycoside Formation by Nickel Triflate.” has been accepted for publication in ACS Catalysis. Congratulations to Eric and Tu!
12/2018: Our group paper, “Iridium-Catalyzed Radiosynthesis of Branched Allylic [18F]Fluorides.” has been accepted for publication in Organic Letters. Congratulations to Alex and Jason!
12/2018: Our group paper: Specific Inhibition of Heparanase by Glycopolymer with Well-Defined Sulfation Pattern Prevents Breast Cancer Metastasis in Mice.” Has been accepted for publication in ACS Applied Materials and Interfaces. Congratulations to Ravi and Eric!
12/2018: The lab welcomes first year graduate student Madhawee Arachchi!
11/2018: Congratulations to Eric Sletten for successfully defending his Ph.D. thesis. Best of luck with your new adventure in the lab of Prof. Peter Seeberger at Max Planck Institute, Dr. Sletten!