Bipolar disorder (BD) is a neurological disease marked by bouts of depression and mania. Valproate and lithium, two drugs that have been used in BD treatment, have been shown to deplete inositol via different mechanisms. Chronic valproate treatment decreases mitochondrial activity and causes upregulation of some glycolytic pathway enzymes. The inositol biosynthetic pathway and the glycolytic pathway overlap due to their shared use of glucose-6-phosphate as substrate. My research focuses on the effects of increased energy demand on inositol synthesis resulting from the overlap of these pathways.
More about Chisom:
I am from Enugu State, Nigeria. I completed my bachelor’s in Microbiology from the University of Nigeria. I sojourned to Japan, where I obtained my master’s in biotechnology from Osaka University. I like to hang out with friends in my free time, play table tennis, visit new places, and meet people. I believe that the fastest way to tour the world is to meet people from different countries. Most importantly, life would not be complete without watching European football!
