5/15/2024: Publication alert – our latest primary research article entitled “Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells” has been accepted for publication in Scientific Reports!

Dr. Zhuqing Liang publishes yet another article detailing the complex interplay between cardiolipin and pyruvate dehydrogenase! This research details a new mechanism whereby cardiolipin-deficiency leads to decreased pyruvate dehydrogenase activity through the genetic regulation of pyruvate dehydrogenase kinase 4. View Read More …

5/1/2024: Dr. Zhuqing Liang and PhD candidate Chisom Onu both gave 15 minutes talks at the 11th annual Lipids@Wayne symposium!

Dr. Zhuqing Liang gave a 15 minute presentation entitled “Dual mechanisms contributing to pyruvate dehydrogenase activity deficiency in a Barth syndrome cell model”. Dr. Liang’s presentation centered around describing two mechanisms by which cardiolipin-deficiency alters the activity of pyruvate dehydrogenase. Read More …