This review article, written by PhD student Mohamed Chakkour, has been published in The Journal of Biological Chemistry! In this article, Mohamed details the intricate and diverse roles of the IP6K1 protein in mammalian cell physiology. View article here: https://doi.org/10.1016/j.jbc.2024.107116
3/2/2024: Greenberg lab students Justina Thomas, Michael Adu, and Vikalp Kumar give tours of the Greenberg lab to prospective students
2/29/2024: Congratulations to our newest Ph.D., Dr. Kendall Case!
Dr. Kendall Case has successfully defended his dissertation entitled “Valproate-induced inositol depletion is a consequence of reduced MIPS expression mediated by the Henry regulatory circuit”. Dr. Case’s work has focused on elucidating the mechanism of inositol depletion by valproate, a Read More …
1/26/2024: Publication alert – our latest research article entitled “Decreased pyruvate dehydrogenase activity in Tafazzin-deficient cells is caused by dysregulation of pyruvate dehydrogenase phosphatase 1 (PDP1)” has been accepted for publication in The Journal of Biological Chemistry!
This research, carried out primarily by Dr. Zhuqing Liang, utilized genetic and biochemical approaches to elucidate one of the mechanisms underlying decreased pyruvate dehydrogenase (PDH) activity in Tafazzin-deficient models of Barth syndrome (BTHS). This mechanism could help explain how cardiolipin Read More …
1/10/2024: Congratulations to Monica Pan for gaining admission to MIT!
Congratulations to Monica Pan on her admission to the MIT biology program! Monica, currently a high school student at Novi High School, volunteered in the Greenberg lab during the summer of 2023. Monica was mentored by Vikalp Kumar, a Greenberg Read More …
12/23/2023: Welcome to the lab, Justina Thomas! PhD student Justina Thomas joins the Greenberg lab.
12/16/2023: Dr. Zhuqing Liang and Dr. Linh Vo walk across the stage at WSU commencement ceremony alongside other WSU Biological Sciences graduates
The WSU Biological Sciences department was well represented in WSU’s 2023 winter commencement ceremony. Congratulations to Greenberg lab members Dr. Zhuqing Liang (left) and Dr. Linh Vo (center left), who walked across the stage on Saturday. A big shout out Read More …
12/15/2023: PhD students Mohamed Chakkour and Chisom Onu snag first place in the graduate category for The Science Coalition’s #FundItForward video challenge!
Mohamed and Chisom’s video highlights the need for studying the therapeutic mechanisms of bipolar disorder drugs in order to develop more efficacious treatments for this prevalent and debilitating illness. View the video here!
11/30/2023: article alert – “Trailblazing Ph.D. graduate appreciates personal growth at Wayne State” highlights the tremendous achievements of Dr. Zhuqing Liang!
The article entitled ” Trailblazing Ph.D. graduate appreciates personal growth at Wayne State” details all of Dr. Zhuqing Liang’s great achievements during her time as a PhD student in the Greenberg lab. To view the article click here. To view Read More …
11/23/2023: Publication alert – our research article entitled “Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome” is published in Nature Metabolism!
This highly collaborative, cross-disciplinary study provides an exciting new framework for understanding the potential cause of Barth syndrome! This research, which utilized genetic, biophysical, lipidomic, and computational approaches, as well as a wide array of Barth syndrome research models, addresses Read More …