5/15/2024: Publication alert – our latest primary research article entitled “Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells” has been accepted for publication in Scientific Reports!

Dr. Zhuqing Liang publishes yet another article detailing the complex interplay between cardiolipin and pyruvate dehydrogenase! This research details a new mechanism whereby cardiolipin-deficiency leads to decreased pyruvate dehydrogenase activity through the genetic regulation of pyruvate dehydrogenase kinase 4. View Read More …