This review article, written by PhD student Mohamed Chakkour, has been published in The Journal of Biological Chemistry! In this article, Mohamed details the intricate and diverse roles of the IP6K1 protein in mammalian cell physiology. View article here: https://doi.org/10.1016/j.jbc.2024.107116
3/2/2024: Greenberg lab students Justina Thomas, Michael Adu, and Vikalp Kumar give tours of the Greenberg lab to prospective students
2/29/2024: Congratulations to our newest Ph.D., Dr. Kendall Case!
Dr. Kendall Case has successfully defended his dissertation entitled “Valproate-induced inositol depletion is a consequence of reduced MIPS expression mediated by the Henry regulatory circuit”. Dr. Case’s work has focused on elucidating the mechanism of inositol depletion by valproate, a Read More …
1/26/2024: Publication alert – our latest research article entitled “Decreased pyruvate dehydrogenase activity in Tafazzin-deficient cells is caused by dysregulation of pyruvate dehydrogenase phosphatase 1 (PDP1)” has been accepted for publication in The Journal of Biological Chemistry!
This research, carried out primarily by Dr. Zhuqing Liang, utilized genetic and biochemical approaches to elucidate one of the mechanisms underlying decreased pyruvate dehydrogenase (PDH) activity in Tafazzin-deficient models of Barth syndrome (BTHS). This mechanism could help explain how cardiolipin Read More …
1/10/2024: Congratulations to Monica Pan for gaining admission to MIT!
Congratulations to Monica Pan on her admission to the MIT biology program! Monica, currently a high school student at Novi High School, volunteered in the Greenberg lab during the summer of 2023. Monica was mentored by Vikalp Kumar, a Greenberg Read More …